This page contains data and other supplementary material for the paper "Mapping gene expression between two Xenopus species: developmental flexibility and evolutionary constraints" by Itai Yanai, Leonid Peshkin, Paul Jorgensen and Marc Kirschner, 2010.

The Supplementary Tabele S1 is available as compresed Excel spreadsheet: Table_S1.xlsx

On the left two female frogs (X. laevis and X. tropicalis) are shown labeled by the blue and green dots, respectively. On the right we illustrate "heterochrony" - a transcriptional shift across species. The abscissa shows developmental stage, the ordinate shows normalized mRNA abundance in log(10) scale. Below we show numbered developmental stages from the normal table. Morphological changes among species arise in large part by modifications in gene regulation throughout the development of the organism, however little is known regarding the propensity for variation in gene regulation as a function of developmental time.

Try our favorite genes:

Conserved
17290 - Chordin
11272 - BMP7
715 - HOXA1
17016 - ZAR1

Convergence
18095 - GREM1
20007 - PARS2

Heterometry
1856 - GLI3
15485 - MYC

Heterochrony
3737 - CPN1
25857 - CHST9

Maternal/Zygotic
shift
25345 - KRT12
25052 - KRT19

Enter the suffix of ENSXETG:

To find ENS gene ID:

To find ID for your favorite gene in our species of reference - X. tropicalis you should begin by searching the Ensembl. Alas, frog annotations are far from perfect, so you might have to go as low as taking a sequence and BLAST-ing it at Enslemb server against X. tropicalis, selecting the right hit and taking the last significant digits from its ID. For example ENSXETG00000014526 becomes 14526, ENSXETG00000001070 becomes 1070, etc. An alternative resource is Uniprot, which often provides pre-computed Ensembl homologues (search term organism:"Xenopus tropicalis [8364]"). Note that we do not have data for some genes, entering such missing gene ID will result in nothing displayed.

Designed and Implemented by Leon Peshkin, using Google Flot, Jul 2010